MS-PEG4-t-butyl ester

Modify Date: 2024-01-29 15:19:57

MS-PEG4-t-butyl ester Structure
MS-PEG4-t-butyl ester structure
Common Name MS-PEG4-t-butyl ester
CAS Number 1024602-74-1 Molecular Weight 356.43
Density N/A Boiling Point N/A
Molecular Formula C14H28O8S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MS-PEG4-t-butyl ester


MS-PEG4-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name MS-PEG4-t-butyl ester

 MS-PEG4-t-butyl ester Biological Activity

Description MS-PEG4-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C14H28O8S
Molecular Weight 356.43