PF-06885249

Modify Date: 2024-01-11 17:33:16

PF-06885249 Structure
PF-06885249 structure
Common Name PF-06885249
CAS Number 1467059-70-6 Molecular Weight 345.783
Density N/A Boiling Point N/A
Molecular Formula C17H16ClN3O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PF-06885249


PF-249 is a potent, selective AMPK β1-containing complexes activator; increases the phosphorylation of the AMPK substrate ACC at S79 with EC50 of 296 nM, potently inhibits de novo lipogenesis (IC50=15 nM) in primary rat hepatocytes.

 Names

Name PF-249

 PF-06885249 Biological Activity

Description PF-249 is a potent, selective AMPK β1-containing complexes activator; increases the phosphorylation of the AMPK substrate ACC at S79 with EC50 of 296 nM, potently inhibits de novo lipogenesis (IC50=15 nM) in primary rat hepatocytes.
References References 1. Cokorinos EC, et al. Cell Metab. 2017 May 2;25(5):1147-1159. View Related Products by Target AMPK

 Chemical & Physical Properties

Molecular Formula C17H16ClN3O3
Molecular Weight 345.783
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