Boc-L-Cyclobutylglycine

Modify Date: 2025-08-25 11:55:11

Boc-L-Cyclobutylglycine Structure
Boc-L-Cyclobutylglycine structure
 Common Name Boc-L-Cyclobutylglycine
CAS Number 155905-77-4 Molecular Weight 229.273
Density 1.2±0.1 g/cm3 Boiling Point 379.1±25.0 °C at 760 mmHg
Molecular Formula C11H19NO4 Melting Point N/A
MSDS N/A Flash Point 183.1±23.2 °C

 Use of Boc-L-Cyclobutylglycine


Boc-L-cyclobutylglycine is a glycine derivative that can be used for PI3K inhibitor synthesis[1].

 Names

Name (S)-2-((tert-Butoxycarbonyl)amino)-2-cyclobutylacetic acid
Synonym More Synonyms

 Boc-L-Cyclobutylglycine Biological Activity

Description Boc-L-cyclobutylglycine is a glycine derivative that can be used for PI3K inhibitor synthesis[1].
Related Catalog
References

[1]. Kim YS, et al. Synthesis and biological evaluation of novel purinyl quinazolinone derivatives as PI3Kδ-specific inhibitors for the treatment of hematologic malignancies. Bioorg Med Chem. 2021 Sep 1;45:116312.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 379.1±25.0 °C at 760 mmHg
Molecular Formula C11H19NO4
Molecular Weight 229.273
Flash Point 183.1±23.2 °C
Exact Mass 229.131409
PSA 75.63000
LogP 2.03
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.501

 Safety Information

Hazard Codes Xi
HS Code 2924299090

 Precursor & DownStream

Precursor  2

DownStream  0

 Customs

HS Code 2924299090
Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

Boc-L-Cyclobutylglycine
Cyclobutaneacetic acid, α-[[(1,1-dimethylethoxy)carbonyl]amino]-, (αS)-
(S)-tert-Butoxycarbonylamino-cyclobutyl-acetic acid
(2S)-Cyclobutyl({[(2-methyl-2-propanyl)oxy]carbonyl}amino)acetic acid
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