G244-LM

Modify Date: 2024-07-21 16:34:23

G244-LM Structure
G244-LM structure
Common Name G244-LM
CAS Number 1563007-08-8 Molecular Weight 406.522
Density 1.5±0.1 g/cm3 Boiling Point N/A
Molecular Formula C18H22N4O3S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of G244-LM


G244-LM is a potent and specific inhibitor of tankyrase 1/2 that inhibits Wnt signaling[1].

 Names

Name 2-{4-[2-(Methylsulfonyl)phenyl]-1-piperazinyl}-3,5,7,8-tetrahydro-4H-thiopyrano[4,3-d]pyrimidin-4-one
Synonym More Synonyms

 G244-LM Biological Activity

Description G244-LM is a potent and specific inhibitor of tankyrase 1/2 that inhibits Wnt signaling[1].
Related Catalog
References

[1]. Lau T, et al. A novel tankyrase small-molecule inhibitor suppresses APC mutation-driven colorectal tumor growth. Cancer Res. 2013 May 15;73(10):3132-44.

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Molecular Formula C18H22N4O3S2
Molecular Weight 406.522
Exact Mass 406.113342
LogP 0.04
Index of Refraction 1.727

 Safety Information

Hazard Codes Xi

 Synonyms

2-{4-[2-(Methylsulfonyl)phenyl]-1-piperazinyl}-3,5,7,8-tetrahydro-4H-thiopyrano[4,3-d]pyrimidin-4-one
4H-Thiopyrano[4,3-d]pyrimidin-4-one, 3,5,7,8-tetrahydro-2-[4-[2-(methylsulfonyl)phenyl]-1-piperazinyl]-
G244-LM
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