RIPK1-IN-13

Modify Date: 2025-08-29 21:22:34

RIPK1-IN-13 Structure
RIPK1-IN-13 structure
Common Name RIPK1-IN-13
CAS Number 1574547-67-3 Molecular Weight 397.85
Density N/A Boiling Point N/A
Molecular Formula C21H20ClN3O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of RIPK1-IN-13


RIPK1-IN-13 (Compound 8) is a potent inhibitor of RIPK1 with an IC50 value of 1139 nM. RIPK1-IN-13 blocks the activation of the necroptosis pathway via the inhibition of RIPK1. RIPK1-IN-13 has the potential for the research of inflammation diseases[1].

 Names

Name RIPK1-IN-13

 RIPK1-IN-13 Biological Activity

Description RIPK1-IN-13 (Compound 8) is a potent inhibitor of RIPK1 with an IC50 value of 1139 nM. RIPK1-IN-13 blocks the activation of the necroptosis pathway via the inhibition of RIPK1. RIPK1-IN-13 has the potential for the research of inflammation diseases[1].
Related Catalog
References

[1]. Niu A, et al. Discovery of novel 2,8-diazaspiro[4.5]decan-1-one derivatives as potent RIPK1 kinase inhibitors. Bioorg Med Chem. 2022 Apr 1;59:116686.

 Chemical & Physical Properties

Molecular Formula C21H20ClN3O3
Molecular Weight 397.85
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