SARS-CoV-2-IN-15

Modify Date: 2024-04-06 21:31:16

SARS-CoV-2-IN-15 structure	Common Name	SARS-CoV-2-IN-15
	CAS Number	1580-42-3	Molecular Weight	315.67
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₄H₉ClF₃NO₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of SARS-CoV-2-IN-15

SARS-CoV-2-IN-15 (compound 11) is a potent inhibitor of SARS-CoV-2 with an IC50 of 0.49 μM. SARS-CoV-2-IN-15 is a niclosamide analogue. SARS-CoV-2-IN-15 contains higher stability in human plasma and liver S9 enzymes assay than niclosamide, which can improve bioavailability and half-life when administered orally[1].

Name	SARS-CoV-2-IN-15

Description	SARS-CoV-2-IN-15 (compound 11) is a potent inhibitor of SARS-CoV-2 with an IC50 of 0.49 μM. SARS-CoV-2-IN-15 is a niclosamide analogue. SARS-CoV-2-IN-15 contains higher stability in human plasma and liver S9 enzymes assay than niclosamide, which can improve bioavailability and half-life when administered orally[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> SARS-CoV
References	[1]. Juang YP, et al. Design, synthesis and biological evaluations of niclosamide analogues against SARS-CoV-2. Eur J Med Chem. 2022 May 5;235:114295.

Molecular Formula	C₁₄H₉ClF₃NO₂
Molecular Weight	315.67

SARS-CoV-2-IN-15

Use of SARS-CoV-2-IN-15

Names

SARS-CoV-2-IN-15 Biological Activity

Chemical & Physical Properties