PF-05388169

Modify Date: 2024-09-21 21:40:18

PF-05388169 Structure
PF-05388169 structure
Common Name PF-05388169
CAS Number 1604034-78-7 Molecular Weight 391.420
Density 1.3±0.1 g/cm3 Boiling Point 640.7±55.0 °C at 760 mmHg
Molecular Formula C22H21N3O4 Melting Point N/A
MSDS N/A Flash Point 341.3±31.5 °C

 Use of PF-05388169


A potent, selective IRAK4 inhibitor with IC50 of 0.094 nM, >500-fold selectivity over IRAK1 (IC50=65 nM).

 Names

Name 2-Methoxy-3-[2-(2-methoxyethoxy)ethoxy]-7H-indolo[2,3-c]quinoline-9-carbonitrile
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 640.7±55.0 °C at 760 mmHg
Molecular Formula C22H21N3O4
Molecular Weight 391.420
Flash Point 341.3±31.5 °C
Exact Mass 391.153198
LogP 2.58
Vapour Pressure 0.0±1.9 mmHg at 25°C
Index of Refraction 1.672

 Synonyms

7H-Indolo[2,3-c]quinoline-9-carbonitrile, 2-methoxy-3-[2-(2-methoxyethoxy)ethoxy]-
2-Methoxy-3-[2-(2-methoxyethoxy)ethoxy]-7H-indolo[2,3-c]quinoline-9-carbonitrile
PF-05388169
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