PF-06256142

Modify Date: 2025-08-26 18:50:12

PF-06256142 Structure
PF-06256142 structure
Common Name PF-06256142
CAS Number 1609583-14-3 Molecular Weight 356.38
Density N/A Boiling Point N/A
Molecular Formula C21H16N4O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PF-06256142


PF-06256142 is a potent and selective orthosteric agonist of the D1 receptor, with D1 EC50=30 nM and D1 binding Ki = 12 nM.

 Names

Name PF-06256142

 PF-06256142 Biological Activity

Description PF-06256142 is a potent and selective orthosteric agonist of the D1 receptor, with D1 EC50=30 nM and D1 binding Ki = 12 nM.
Related Catalog
References

[1]. Davoren JE, et al. Discovery and Lead Optimization of Atropisomer D1 Agonists with Reduced Desensitization. J Med Chem. 2018 Nov 15.

 Chemical & Physical Properties

Molecular Formula C21H16N4O2
Molecular Weight 356.38
InChIKey HWAIAGZSWHOLLK-UHFFFAOYSA-N
SMILES Cc1cc(Oc2nccc3occc23)ccc1-c1c(C)ncc2nccn12
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