7-hydroxycoumarinyl-γ-Linolenate
Modify Date: 2024-01-14 18:50:53
7-hydroxycoumarinyl-γ-Linolenate structure
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Common Name | 7-hydroxycoumarinyl-γ-Linolenate | ||
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| CAS Number | 161180-12-7 | Molecular Weight | 422.556 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 563.5±50.0 °C at 760 mmHg | |
| Molecular Formula | C27H34O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 279.3±28.5 °C | |
Use of 7-hydroxycoumarinyl-γ-Linolenate7-Hydroxycoumarinyl-γ-linolenate is a cytosolic phospholipase A2 (cPLA2) fluorogenic substrate. 7-Hydroxycoumarinyl-γ-linolenate can be used to monitor the enzymatic activity of cPLA2[1]. |
| Name | (2-oxochromen-7-yl) octadeca-6,9,12-trienoate |
|---|---|
| Synonym | More Synonyms |
| Description | 7-Hydroxycoumarinyl-γ-linolenate is a cytosolic phospholipase A2 (cPLA2) fluorogenic substrate. 7-Hydroxycoumarinyl-γ-linolenate can be used to monitor the enzymatic activity of cPLA2[1]. |
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| Related Catalog | |
| In Vitro | Guidelines (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs). cPLA2α activity assay[1][2]: 1. Sonicate 200 μL of 1,2-O-tetradecyl-sn-glycero-3-phosphocholine (DTPC)/Triton X-100 high-affinity mixed micelle solution containing 960 μM Triton X-100 (HY-Y1883A), 60 μM DTPC, 50 μM 7-hydroxycoumarinyl-γ-linolenate, 50 mM N-2-hydroxyethylpiperazine-N-2-ethane sulfonic acid buffer (pH = 7.2), 0.3 mM EDTA (HY-Y0682), 1 mM CaCl2 and 300 mM KCl. 2. Monitoring the hydrolysis of 7-hydroxycoumarinyl-γ-linolenate continuously with excitation at 360 nm and emission at 460 nm. 3. The formation of 7-hydroxycoumarin was monitored by fluorospectrometer. |
| References |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 563.5±50.0 °C at 760 mmHg |
| Molecular Formula | C27H34O4 |
| Molecular Weight | 422.556 |
| Flash Point | 279.3±28.5 °C |
| Exact Mass | 422.245697 |
| PSA | 56.51000 |
| LogP | 7.58 |
| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
| Index of Refraction | 1.540 |
| 2-Oxo-2H-chromen-7-yl (6Z,9Z,12Z)-6,9,12-octadecatrienoate |
| 6,9,12-Octadecatrienoic acid, 2-oxo-2H-1-benzopyran-7-yl ester, (6E,9E,12E)- |
| 2-Oxo-2H-chromen-7-yl (6E,9E,12E)-6,9,12-octadecatrienoate |
| 6,9,12-Octadecatrienoic acid, 2-oxo-2H-1-benzopyran-7-yl ester, (6Z,9Z,12Z)- |
| 7-hydroxycoumarinyl--Linolenate |