LEI-106
Modify Date: 2025-08-25 11:59:41
LEI-106 structure
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Common Name | LEI-106 | ||
|---|---|---|---|---|
| CAS Number | 1620582-23-1 | Molecular Weight | 481.561 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 664.1±65.0 °C at 760 mmHg | |
| Molecular Formula | C26H27NO6S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 355.4±34.3 °C | |
Use of LEI-106LEI-106 is a potent, dual sn-1-Diacylglycerol lipase α (DAGL-α)/ABHD6 inhibitor with an IC50 of 18 nM for DAGL-α and a Ki of 0.8 μM for ABHD6. LEI-106 inhibits the hydrolysis of [14C]-sn-1-oleoyl-2-arachidonoyl-glycerol, the natural substrate of DAGL-α, with a Ki of 0.7 μM[1]. |
| Name | LEI-106 |
|---|---|
| Synonym | More Synonyms |
| Description | LEI-106 is a potent, dual sn-1-Diacylglycerol lipase α (DAGL-α)/ABHD6 inhibitor with an IC50 of 18 nM for DAGL-α and a Ki of 0.8 μM for ABHD6. LEI-106 inhibits the hydrolysis of [14C]-sn-1-oleoyl-2-arachidonoyl-glycerol, the natural substrate of DAGL-α, with a Ki of 0.7 μM[1]. |
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| Related Catalog | |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 664.1±65.0 °C at 760 mmHg |
| Molecular Formula | C26H27NO6S |
| Molecular Weight | 481.561 |
| Flash Point | 355.4±34.3 °C |
| Exact Mass | 481.155914 |
| LogP | 7.75 |
| Vapour Pressure | 0.0±2.1 mmHg at 25°C |
| Index of Refraction | 1.607 |
| N-[(2,2-Dimethyl-3,4-dihydro-2H-chromen-6-yl)sulfonyl]-N-(4-phenoxybenzyl)glycine |
| Glycine, N-[(3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-6-yl)sulfonyl]-N-[(4-phenoxyphenyl)methyl]- |
| LEI-106 |