BRCA1-IN-2

Modify Date: 2024-01-09 10:04:22

BRCA1-IN-2 Structure
BRCA1-IN-2 structure
Common Name BRCA1-IN-2
CAS Number 1622262-55-8 Molecular Weight 544.54
Density N/A Boiling Point N/A
Molecular Formula C26H33N4O7P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BRCA1-IN-2


BRCA1-IN-2 (compound 15) is a cell-permeable protein-protein interaction (PPI) inhibitor for BRCA1 with an IC50 of 0.31 μM and a Kd of 0.3 μM, which shows antitumor activities via the disruption of BRCA1 (BRCT)2/protein interactions[1].

 Names

Name BRCA1-IN-2

 BRCA1-IN-2 Biological Activity

Description BRCA1-IN-2 (compound 15) is a cell-permeable protein-protein interaction (PPI) inhibitor for BRCA1 with an IC50 of 0.31 μM and a Kd of 0.3 μM, which shows antitumor activities via the disruption of BRCA1 (BRCT)2/protein interactions[1].
Related Catalog
Target

IC50: 0.31 μM (BRCA1)[1] Kd: 0.3 μM (BRCA1)[1]

References

[1]. Na Z, et al. Protein-Protein Interaction Inhibitors of BRCA1 Discovered Using Small Molecule Microarrays. Methods Mol Biol. 2017;1518:139-156.

 Chemical & Physical Properties

Molecular Formula C26H33N4O7P
Molecular Weight 544.54
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