305372-39-8

305372-39-8 structure

Name: Biotin-PEG2-Mal
Chemical Name: N-[2-[2-[2-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]ethoxy]ethoxy]ethyl]-5-(2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl)pentanamide
CAS Number: 305372-39-8
Molecular Formula: C₂₃H₃₅N₅O₇S
Molecular Weight: 525.618
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-11-23 12:12:16
Modify Date: 2024-01-04 21:36:49
Biotin-PEG2-Mal is a PEG-based PROTAC linker can be used in the synthesis of PROTAC.

Name	N-[2-[2-[2-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]ethoxy]ethoxy]ethyl]-5-(2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl)pentanamide
Synonyms	N-Biotinyl-N'-(3-maleimidopropionyl)-3,6-dioxaoctane-1,8-diamine 1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[2-[2-[2-[[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]ethoxy]ethoxy]ethyl]hexahydro-2-oxo-, (3aS,4S,6aR)- B3174 N-{2-[2-(2-{[3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanoyl]amino}ethoxy)ethoxy]ethyl}-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide Maleimide-PEG2-Biotin

Description	Biotin-PEG2-Mal is a PEG-based PROTAC linker can be used in the synthesis of PROTAC.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Hazard Codes	Xi