N-Boc-PEG3-bromide

Modify Date: 2024-01-09 11:49:42

N-Boc-PEG3-bromide Structure
N-Boc-PEG3-bromide structure
Common Name N-Boc-PEG3-bromide
CAS Number 165963-71-3 Molecular Weight 312.201
Density 1.3±0.1 g/cm3 Boiling Point 382.8±27.0 °C at 760 mmHg
Molecular Formula C11H22BrNO4 Melting Point N/A
MSDS N/A Flash Point 185.3±23.7 °C

 Use of N-Boc-PEG3-bromide


N-Boc-PEG3-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

 Names

Name 2-[2-(2-t-Boc-aminoethoxy]ethoxy]ethyl Bromide
Synonym More Synonyms

 N-Boc-PEG3-bromide Biological Activity

Description N-Boc-PEG3-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References

[1]. Alex Cortez, et al. Antibody conjugates comprising toll-like receptor agonist and combination therapies. WO2018198091A1.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 382.8±27.0 °C at 760 mmHg
Molecular Formula C11H22BrNO4
Molecular Weight 312.201
Flash Point 185.3±23.7 °C
Exact Mass 311.073212
PSA 60.28000
LogP 1.75
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.472
Storage condition 2-8°C

 Safety Information

Hazard Codes Xi

 Synonyms

Carbamic acid, N-[2-[2-(2-bromoethoxy)ethoxy]ethyl]-, 1,1-dimethylethyl ester
tert-butyl N-[2-[2-(2-bromoethoxy)ethoxy]ethyl]carbamate
2-Methyl-2-propanyl {2-[2-(2-bromoethoxy)ethoxy]ethyl}carbamate