RP 001 hydrochloride
Modify Date: 2024-01-15 13:57:16
RP 001 hydrochloride structure
|
Common Name | RP 001 hydrochloride | ||
|---|---|---|---|---|
| CAS Number | 1781880-34-9 | Molecular Weight | 468.93 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C24H25ClN4O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of RP 001 hydrochlorideRP-001 hydrochloride is a picomolar short-acting S1P1 (EDG1) selective agonist, with an EC50 of 9 pM. RP-00 hydrochloride induces internalization and polyubiquitination of S1P1. RP-001 hydrochloride has little activity on S1P2-S1P4 and only moderate affinity for S1P5[1]. |
| Name | RP-001 hydrochloride |
|---|
| Description | RP-001 hydrochloride is a picomolar short-acting S1P1 (EDG1) selective agonist, with an EC50 of 9 pM. RP-00 hydrochloride induces internalization and polyubiquitination of S1P1. RP-001 hydrochloride has little activity on S1P2-S1P4 and only moderate affinity for S1P5[1]. |
|---|---|
| Related Catalog | |
| In Vitro | RP-001 hydrochloride elicits dose-dependent lymphopenia of CD4+ T cells. RP-001 hydrochloride induces acute lymphopenia with rapid recovery to untreated levels[1]. |
| In Vivo | RP-001 hydrochloride causes dose-dependent rapid lymphopenia with an EC50 of 0.03 mg/kg[1]. |
| References |
| Molecular Formula | C24H25ClN4O4 |
|---|---|
| Molecular Weight | 468.93 |