CK1-IN-1

Modify Date: 2025-09-12 01:19:17

CK1-IN-1 Structure
CK1-IN-1 structure
Common Name CK1-IN-1
CAS Number 1784751-20-7 Molecular Weight 383.39
Density N/A Boiling Point N/A
Molecular Formula C24H15F2N3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CK1-IN-1


CK1-IN-1 is a casein kinase 1 (CK1) inhibitor extracted from patent WO2015119579A1, compound 1c, has IC50s of 15 nM, 16 nM, 73 nM for CK1δ, and CK1ε, p38σ MAPK, respectively[1].

 Names

Name CK1-IN-1

 CK1-IN-1 Biological Activity

Description CK1-IN-1 is a casein kinase 1 (CK1) inhibitor extracted from patent WO2015119579A1, compound 1c, has IC50s of 15 nM, 16 nM, 73 nM for CK1δ, and CK1ε, p38σ MAPK, respectively[1].
Related Catalog
Target

CKIδ:15 nM (IC50)

CK1ϵ:16 nM (IC50)

References

[1]. Filip LACO,et al. 2,4,5-tri-substituted azole-based casein kinase 1 inhibitors as inducers for cardiomyogenesis. WO2015119579A1.

 Chemical & Physical Properties

Molecular Formula C24H15F2N3
Molecular Weight 383.39
InChIKey PUQAFIILJICJRR-UHFFFAOYSA-N
SMILES Fc1ccc(-c2nc(-c3ccc4ccccc4c3F)[nH]c2-c2ccncc2)cc1
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