CDK4/6-IN-2

Modify Date: 2024-01-11 00:08:21

CDK4/6-IN-2 structure	Common Name	CDK4/6-IN-2
	CAS Number	1800506-48-2	Molecular Weight	506.59
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₇H₃₂F₂N₈	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of CDK4/6-IN-2

CDK4/6-IN-2 is a potent CDK4 and CDK6 inhibitor extracted from patent US20180000819A1, Compound 1, has IC50s of 2.7 and 16 nM for CDK4 and CDK6, respectively[1].

Name	CDK4/6-IN-2

Description	CDK4/6-IN-2 is a potent CDK4 and CDK6 inhibitor extracted from patent US20180000819A1, Compound 1, has IC50s of 2.7 and 16 nM for CDK4 and CDK6, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> CDK
Target	CDK4:2.7 nM (IC50) CDK6:16 nM (IC50)
In Vitro	CDK4/6-IN-2 inhibits H358, H441, PC3, MV-4-11, JeKo-1, SW780, and HGC-27 cells with IC50s of 290.9, 147.8, 260.5, 139, 36.98, 162.5, and 316.4 nM, respectively[1].
References	[1]. Frank Wu, et al. Kinase inhibitor and use thereof. US20180000819A1.

Molecular Formula	C₂₇H₃₂F₂N₈
Molecular Weight	506.59

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: CDK4/6-IN-2
Price: Check
Purity: 99.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

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Price: ￥3901/10 mM * 1 mL in DMSO

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CDK4/6-IN-2

Use of CDK4/6-IN-2

Names

CDK4/6-IN-2 Biological Activity

Chemical & Physical Properties