CDK4/6-IN-8

Modify Date: 2024-01-14 15:28:01

CDK4/6-IN-8 structure	Common Name	CDK4/6-IN-8
	CAS Number	2649120-22-7	Molecular Weight	398.37
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₈H₁₈N₆O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of CDK4/6-IN-8

CDK4/6-IN-8 (Compound 7p) is a selective CDK4 and CDK6 inhibitor with IC50 values of 5.01 nM and 3.97 nM, respectively[1].

Name	CDK4/6-IN-8

Description	CDK4/6-IN-8 (Compound 7p) is a selective CDK4 and CDK6 inhibitor with IC50 values of 5.01 nM and 3.97 nM, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> CDK
Target	CDK4:5.01 nM (IC50) CDK6:3.97 nM (IC50)
In Vitro	CDK4/6-IN-8 (Compound 7p) (0-656.1 µM, 48 h) shows anti-breast cancer activity[1]. Cell Viability Assay[1] Cell Line: MCF-7 Concentration: 0.1, 0.3, 0.9, 2.7, 8.1, 24.3, 72.9, 218.7 and 656.1 µM Incubation Time: 48 h Result: Inhibited cell viability with an IC50 of 2.8 μM.
References	[1]. Liang JW, et al. Synthesis and identification of a novel skeleton of N-(pyridin-3-yl) proline as a selective CDK4/6 inhibitor with anti-breast cancer activities. Bioorg Chem. 2022 Feb;119:105547.

Molecular Formula	C₁₈H₁₈N₆O₅
Molecular Weight	398.37

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Palmitic acid
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com