CDK4/6-IN-5
Modify Date: 2025-09-13 20:06:53
CDK4/6-IN-5 structure
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Common Name | CDK4/6-IN-5 | ||
|---|---|---|---|---|
| CAS Number | 2380321-50-4 | Molecular Weight | 527.01 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H28ClFN6O4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of CDK4/6-IN-5CDK4/6-IN-5 is a potent CDK4 and CDK6 inhibitor with Kis of 0.2 and 4.4 nM for CDK4/Cyclin D1 and CDK6/Cyclin D3, respectively[1]. (from patent WO2019207463A1 example A93). |
| Name | CDK4/6-IN-5 |
|---|
| Description | CDK4/6-IN-5 is a potent CDK4 and CDK6 inhibitor with Kis of 0.2 and 4.4 nM for CDK4/Cyclin D1 and CDK6/Cyclin D3, respectively[1]. (from patent WO2019207463A1 example A93). |
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| Related Catalog | |
| In Vitro | The CDK4 and CDK6 cell-based IC50s of CDK4/6-IN-5 in JEKO-1 and MV4-1 1 cells are 23.8 and 61.4 nM, respectively[1]. |
| References |
| Molecular Formula | C22H28ClFN6O4S |
|---|---|
| Molecular Weight | 527.01 |
| InChIKey | KSCSDVHAZVSGAW-XHBKTUGNSA-N |
| SMILES | CC(O)c1nc2c(F)cc(-c3nc(NC4CCN(S(C)(=O)=O)CC4O)ncc3Cl)cc2n1C(C)C |