CDK4/6-IN-12
Modify Date: 2025-08-26 10:09:34
CDK4/6-IN-12 structure
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Common Name | CDK4/6-IN-12 | ||
|---|---|---|---|---|
| CAS Number | 2445205-24-1 | Molecular Weight | 238.25 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C12H10N6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of CDK4/6-IN-12CDK4/6-IN-12 is a potent cyclin-dependent kinase 4/6 (CDK4/6) inhibitor. CDK4/6-IN-12 has enzymatic inhibitory activity for CDK4 and CDK6 with IC50 of 592.3 nM and 3090 nM, respectively. CDK4/6-IN-12 can be used for the research of cancer[1]. |
| Name | CDK4/6-IN-12 |
|---|
| Description | CDK4/6-IN-12 is a potent cyclin-dependent kinase 4/6 (CDK4/6) inhibitor. CDK4/6-IN-12 has enzymatic inhibitory activity for CDK4 and CDK6 with IC50 of 592.3 nM and 3090 nM, respectively. CDK4/6-IN-12 can be used for the research of cancer[1]. |
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| Related Catalog | |
| Target |
CDK4:592.3 nM (IC50) CDK6:3090 nM (IC50) |
| In Vitro | CDK4/6-IN-12 (compound 4a) inhibits CDK4 and CDK6 with IC50 of 592.3 nM and 3090 nM, respectively[1]. |
| References |
| Molecular Formula | C12H10N6 |
|---|---|
| Molecular Weight | 238.25 |
| InChIKey | GLDQROMTPTWBPL-UHFFFAOYSA-N |
| SMILES | Cc1cn2c(n1)c(C#N)c(C)c1cnc(N)nc12 |