Aminooxy-PEG3-propargyl

Modify Date: 2024-01-10 09:30:08

Aminooxy-PEG3-propargyl Structure
Aminooxy-PEG3-propargyl structure
Common Name Aminooxy-PEG3-propargyl
CAS Number 1807537-27-4 Molecular Weight 203.236
Density 1.1±0.1 g/cm3 Boiling Point 309.6±32.0 °C at 760 mmHg
Molecular Formula C9H17NO4 Melting Point N/A
MSDS N/A Flash Point 146.4±18.8 °C

 Use of Aminooxy-PEG3-propargyl


Aminooxy-PEG3-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Aminoxy-PEG3-Propargyl
Synonym More Synonyms

 Aminooxy-PEG3-propargyl Biological Activity

Description Aminooxy-PEG3-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Christopher Semko, et al. Rapamycin analogs as mtor inhibitors. WO2018204416A1.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 309.6±32.0 °C at 760 mmHg
Molecular Formula C9H17NO4
Molecular Weight 203.236
Flash Point 146.4±18.8 °C
Exact Mass 203.115753
LogP -0.38
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.461
Storage condition 2-8°C

 Synonyms

AMINOXY-PEG3-PROPARGYL
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