Aminooxy-PEG3-acid

Modify Date: 2024-01-10 12:15:06

Aminooxy-PEG3-acid Structure
Aminooxy-PEG3-acid structure
Common Name Aminooxy-PEG3-acid
CAS Number 1807540-79-9 Molecular Weight 237.250
Density 1.2±0.1 g/cm3 Boiling Point 415.9±40.0 °C at 760 mmHg
Molecular Formula C9H19NO6 Melting Point N/A
MSDS N/A Flash Point 205.3±27.3 °C

 Use of Aminooxy-PEG3-acid


Aminooxy-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Aminoxy-PEG3-acid
Synonym More Synonyms

 Aminooxy-PEG3-acid Biological Activity

Description Aminooxy-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 415.9±40.0 °C at 760 mmHg
Molecular Formula C9H19NO6
Molecular Weight 237.250
Flash Point 205.3±27.3 °C
Exact Mass 237.121231
LogP -1.13
Vapour Pressure 0.0±2.1 mmHg at 25°C
Index of Refraction 1.468

 Synonyms

Propanoic acid, 3-[2-[2-[2-(aminooxy)ethoxy]ethoxy]ethoxy]-
3-(2-{2-[2-(Aminooxy)ethoxy]ethoxy}ethoxy)propanoic acid
MFCD26127821
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