Aminooxy-PEG3-NH-Boc

Modify Date: 2024-01-20 15:38:34

Aminooxy-PEG3-NH-Boc Structure
Aminooxy-PEG3-NH-Boc structure
Common Name Aminooxy-PEG3-NH-Boc
CAS Number 2062663-65-2 Molecular Weight 308.37
Density N/A Boiling Point N/A
Molecular Formula C13H28N2O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Aminooxy-PEG3-NH-Boc


Aminooxy-PEG3-C2-NH-Boc is a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Aminooxy-PEG3-C2-NH-Boc

 Aminooxy-PEG3-NH-Boc Biological Activity

Description Aminooxy-PEG3-C2-NH-Boc is a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C13H28N2O6
Molecular Weight 308.37