Ald-Ph-amido-C2-PEG3-azide

Modify Date: 2024-01-08 22:07:18

Ald-Ph-amido-C2-PEG3-azide Structure
Ald-Ph-amido-C2-PEG3-azide structure
Common Name Ald-Ph-amido-C2-PEG3-azide
CAS Number 1807540-88-0 Molecular Weight 350.370
Density N/A Boiling Point N/A
Molecular Formula C16H22N4O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Ald-Ph-amido-C2-PEG3-azide


Ald-Ph-amido-C2-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Ald-Ph-PEG3-Azide
Synonym More Synonyms

 Ald-Ph-amido-C2-PEG3-azide Biological Activity

Description Ald-Ph-amido-C2-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C16H22N4O5
Molecular Weight 350.370
Exact Mass 350.159027
LogP 0.29

 Safety Information

Hazard Codes Xi

 Synonyms

ALD-PH-PEG3-N3
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