VU 0650786
Modify Date: 2025-11-25 13:51:47
VU 0650786 structure
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Common Name | VU 0650786 | ||
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| CAS Number | 1809085-30-0 | Molecular Weight | 387.80 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C18H15ClFN5O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of VU 0650786VU0650786 is a potent and selective CNS penetrant negative allosteric modulator of metabotropic glutamate receptor subtype 3 (mGlu3), with an IC50 of 392 nM. VU0650786 has antidepressant and anxiolytic activity in rodents[1]. |
| Name | VU0650786 |
|---|
| Description | VU0650786 is a potent and selective CNS penetrant negative allosteric modulator of metabotropic glutamate receptor subtype 3 (mGlu3), with an IC50 of 392 nM. VU0650786 has antidepressant and anxiolytic activity in rodents[1]. |
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| Related Catalog | |
| Target |
mGluR3:392 nM (IC50) |
| References |
| Molecular Formula | C18H15ClFN5O2 |
|---|---|
| Molecular Weight | 387.80 |
| InChIKey | RXRVCJFGSOVYLG-LLVKDONJSA-N |
| SMILES | CC1CN(c2cccnc2F)C(=O)c2cc(COc3ccc(Cl)cn3)nn21 |
| Storage condition | 2-8℃ |