VU 0650786

Modify Date: 2025-11-25 13:51:47

VU 0650786 structure	Common Name	VU 0650786
	CAS Number	1809085-30-0	Molecular Weight	387.80
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₈H₁₅ClFN₅O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of VU 0650786

VU0650786 is a potent and selective CNS penetrant negative allosteric modulator of metabotropic glutamate receptor subtype 3 (mGlu3), with an IC50 of 392 nM. VU0650786 has antidepressant and anxiolytic activity in rodents[1].

Name	VU0650786

Description	VU0650786 is a potent and selective CNS penetrant negative allosteric modulator of metabotropic glutamate receptor subtype 3 (mGlu3), with an IC50 of 392 nM. VU0650786 has antidepressant and anxiolytic activity in rodents[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> mGluR Research Areas >> Neurological Disease
Target	mGluR3:392 nM (IC50)
References	[1]. Engers JL, et al. Discovery of a Selective and CNS Penetrant Negative Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 3 with Antidepressant and Anxiolytic Activity in Rodents. J Med Chem. 2015 Sep 24;58(18):7485-500.

Molecular Formula	C₁₈H₁₅ClFN₅O₂
Molecular Weight	387.80
Storage condition	2-8℃

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: VU0650786
Price: Check
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ShangHai DC Chemicals Co.,Ltd
China
Product Name: VU 0650786
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
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DC Chemicals Limited
China
Product Name: VU 0650786
Price: $950.0/100mg $1900.0/250mg $3800.0/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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VU 0650786

Use of VU 0650786

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VU 0650786 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.