Azido-PEG1-CH2CO2-t-Bu

Modify Date: 2024-01-09 20:53:45

Azido-PEG1-CH2CO2-t-Bu Structure
Azido-PEG1-CH2CO2-t-Bu structure
Common Name Azido-PEG1-CH2CO2-t-Bu
CAS Number 1820717-35-8 Molecular Weight 201.22
Density N/A Boiling Point N/A
Molecular Formula C8H15N3O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azido-PEG1-CH2CO2-t-Bu


Azido-PEG1-C1-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Azido-PEG1-C1-Boc
Synonym More Synonyms

 Azido-PEG1-CH2CO2-t-Bu Biological Activity

Description Azido-PEG1-C1-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C8H15N3O3
Molecular Weight 201.22

 Synonyms

MFCD27635154
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