Azido-PEG1-PFP ester

Modify Date: 2024-03-11 19:18:54

Azido-PEG1-PFP ester Structure
Azido-PEG1-PFP ester structure
Common Name Azido-PEG1-PFP ester
CAS Number 1807505-32-3 Molecular Weight 325.191
Density N/A Boiling Point N/A
Molecular Formula C11H8F5N3O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azido-PEG1-PFP ester


Azido-PEG1-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Azido-PEG1-PFP ester
Synonym More Synonyms

 Azido-PEG1-PFP ester Biological Activity

Description Azido-PEG1-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C11H8F5N3O3
Molecular Weight 325.191
Exact Mass 325.048584
LogP 2.74

 Synonyms

Pentafluorophenyl 3-(2-azidoethoxy)propanoate
MFCD26793775
Propanoic acid, 3-(2-azidoethoxy)-, 2,3,4,5,6-pentafluorophenyl ester
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