L778123 dihydrochloride
Modify Date: 2024-01-06 07:27:31
L778123 dihydrochloride structure
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Common Name | L778123 dihydrochloride | ||
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| CAS Number | 183499-56-1 | Molecular Weight | 478.802 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H22Cl3N5O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of L778123 dihydrochlorideL-778123 is an inhibitor of FPTase and GGPTase-I, which was developed in part because it can completely inhibit Ki-Ras prenylation. The combination of L-778,123 and radiotherapy at dose level 1 showed acceptable toxicity in patients with locally advanced pancreatic cancer. Radiosensitization of a patient-derived pancreatic cancer cell line was observed. |
| Name | L778123 dihydrochloride |
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| Description | L-778123 is an inhibitor of FPTase and GGPTase-I, which was developed in part because it can completely inhibit Ki-Ras prenylation. The combination of L-778,123 and radiotherapy at dose level 1 showed acceptable toxicity in patients with locally advanced pancreatic cancer. Radiosensitization of a patient-derived pancreatic cancer cell line was observed. |
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| Molecular Formula | C22H22Cl3N5O |
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| Molecular Weight | 478.802 |