IRAK4-IN-4

Modify Date: 2024-01-13 11:11:26

IRAK4-IN-4 Structure
IRAK4-IN-4 structure
Common Name IRAK4-IN-4
CAS Number 1850276-58-2 Molecular Weight 340.37
Density N/A Boiling Point N/A
Molecular Formula C22H16N2O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of IRAK4-IN-4


IRAK4-IN-4 is an interleukin-1 receptor–associated kinase 4 (IRAK4) inhibitor extracted from patent CN107163044A, Compound15, has an IC50 of 2.8 nM. IRAK4-IN-4 also inhibits cyclic GMP-AMP synthase (cGAS) with an IC50 of 2.1 nM[1].

 Names

Name IRAK4-IN-4

 IRAK4-IN-4 Biological Activity

Description IRAK4-IN-4 is an interleukin-1 receptor–associated kinase 4 (IRAK4) inhibitor extracted from patent CN107163044A, Compound15, has an IC50 of 2.8 nM. IRAK4-IN-4 also inhibits cyclic GMP-AMP synthase (cGAS) with an IC50 of 2.1 nM[1].
Related Catalog
Target

IC50: 2.8 nM (IRAK4), 2.1 nM (cGAS)[1]

References

[1]. One class has the naphthalene second dione compounds and its derivative of protease modification activities. CN107163044A.

 Chemical & Physical Properties

Molecular Formula C22H16N2O2
Molecular Weight 340.37
Storage condition 2-8°C
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