6-(Chloromethyl)-2,4(1H,3H)-pyrimidinedione

Modify Date: 2024-01-04 12:34:43

6-(Chloromethyl)-2,4(1H,3H)-pyrimidinedione Structure
6-(Chloromethyl)-2,4(1H,3H)-pyrimidinedione structure
Common Name 6-(Chloromethyl)-2,4(1H,3H)-pyrimidinedione
CAS Number 18592-13-7 Molecular Weight 160.558
Density 1.4±0.1 g/cm3 Boiling Point 493.9ºC at 760 mmHg
Molecular Formula C5H5ClN2O2 Melting Point 257 °C (dec.)(lit.)
MSDS Chinese USA Flash Point 252.5ºC
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 6-(chloromethyl)-1H-pyrimidine-2,4-dione
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 493.9ºC at 760 mmHg
Melting Point 257 °C (dec.)(lit.)
Molecular Formula C5H5ClN2O2
Molecular Weight 160.558
Flash Point 252.5ºC
Exact Mass 160.003952
PSA 65.72000
LogP 0.04
Vapour Pressure 2.23E-10mmHg at 25°C
Index of Refraction 1.511

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2933599090

 Customs

HS Code 2933599090
Summary 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles5

More Articles
Synthesis and enzymatic evaluation of pyridinium-substituted uracil derivatives as novel inhibitors of thymidine phosphorylase.

Bioorg. Med. Chem. 10(3) , 525-30, (2002)

A series of water soluble N(1)- and C(6)-substituted uracil pyridinium compounds were prepared as potential inhibitors of thymidine phosphorylase (TP). The C(6)-uracil substituted derivatives were the...

Synthesis and evaluation of 6-methylene-bridged uracil derivatives. Part 1: discovery of novel orally active inhibitors of human thymidine phosphorylase.

Bioorg. Med. Chem. 12(13) , 3431-41, (2004)

A series of novel 6-methylene-bridged uracil derivatives have been prepared as inhibitors of human thymidine phosphorylase (TP). To enhance the in vivo antitumor activity of fluorinated pyrimidine 2'-...

Syntheses of novel heterocycles as anticancer agents.

Bioorg. Med. Chem. 13(10) , 3513-8, (2005)

Several pteridine analogues 4-13, 23-26 have been synthesized and tested in vitro against three cancer cell lines, MCF7 (breast), NCI-H460 (lung) and SF-268 (CNS). All tested pteridines can serve as n...

 Synonyms

6-(chloromethyl)pyrimidine-2,4(1H,3H)-dione
2,4(1H,3H)-Pyrimidinedione, 6-(chloromethyl)-
6-(Chloromethyl)-2,4(1H,3H)-pyrimidinedione
EINECS 242-431-9
6-chloromethylpyrimidine-2,4-dione
6-uracilylmethylchloride
MFCD00466419
6-Chloromethyluracil
6-(Chloromethyl)uracil
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