Ac-Trp-Glu-His-Asp-aldehyde (pseudo acid)

Modify Date: 2024-01-02 12:56:20

Ac-Trp-Glu-His-Asp-aldehyde (pseudo acid) structure	Common Name	Ac-Trp-Glu-His-Asp-aldehyde (pseudo acid)
	CAS Number	189275-71-6	Molecular Weight	611.60
	Density	1.4±0.1 g/cm3	Boiling Point	1250.2±65.0 °C at 760 mmHg
	Molecular Formula	C₂₈H₃₃N₇O₉	Melting Point	N/A
	MSDS	N/A	Flash Point	709.9±34.3 °C

Use of Ac-Trp-Glu-His-Asp-aldehyde (pseudo acid)

Ac-Trp-Glu-His-Asp-Aldehyde is a potent and selective caspase-1 inhibitor with a Ki value of 56 pM[1][2].

Name	ac-wehd-cho
Synonym	More Synonyms

Description	Ac-Trp-Glu-His-Asp-Aldehyde is a potent and selective caspase-1 inhibitor with a Ki value of 56 pM[1][2].
Related Catalog	Signaling Pathways >> Apoptosis >> Caspase Research Areas >> Inflammation/Immunology
Target	Caspase-1:56 pM (Ki)
References	[1]. Kindermann M, et al. Selective and sensitive monitoring of caspase-1 activity by a novel bioluminescent activity-based probe. Chem Biol. 2010 Sep 24;17(9):999-1007. [2]. Rano TA, et al. A combinatorial approach for determining protease specificities: application to interleukin-1beta converting enzyme (ICE). Chem Biol. 1997 Feb;4(2):149-55.

WGK Germany	3

N-ACETYL-TRP-GLU-HIS-ASPARTINAL

N-Acetyl-L-tryptophyl-L-α-glutamyl-N-[(2S)-1-carboxy-3-oxo-2-propanyl]-L-histidinamide

AC-WEHD-ALDEHYDE

PASE-INHIBITOR VIII

Acetyl-tryptyl-glutamyl-histidyl-aspartal

AC-TRP-GLU-HIS-ASP-ALDEHYDE

PASE-1 INHIBITOR VIII

AC-TRP-GLU-HIS-ASP-CHO

N-Acetyl-L-tryptophyl-L-α-glutamyl-N-[(2S)-1-carboxy-3-oxopropan-2-yl]-L-histidinamide

L-Histidinamide, N-acetyl-L-tryptophyl-L-α-glutamyl-N-[(1S)-2-carboxy-1-formylethyl]-

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