Ac-DEVD-pNA
Modify Date: 2025-09-27 16:31:51
Ac-DEVD-pNA structure
|
Common Name | Ac-DEVD-pNA | ||
|---|---|---|---|---|
| CAS Number | 189684-50-2 | Molecular Weight | 638.5 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C26H34N6O13 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Ac-DEVD-pNAAc-DEVD-pNA is a colorimetric substrate for caspase-3 (CPP32) (Km=9.7μM) and related cysteine proteases. |
| Name | Ac-DEVD-pNA(Caspase-3 Substrate) |
|---|
| Description | Ac-DEVD-pNA is a colorimetric substrate for caspase-3 (CPP32) (Km=9.7μM) and related cysteine proteases. |
|---|---|
| In Vitro | Ac-DEVD-pNA is a colorimetric substrate for caspase-3 (CPP32) (Km=9.7μM) and related cysteine proteases. It is also a substrate for caspase-6, caspase-7, caspase-8, and caspase-10. The sequence is based on PARP (poly(ADPribose) polymerase) cleavage site Asp216 for caspase-3. Cleavage is monitored colorimetrically at 405nm. |
| Molecular Formula | C26H34N6O13 |
|---|---|
| Molecular Weight | 638.5 |
| InChIKey | DAOMBBSDYYRHPX-ORGXJRBJSA-N |
| SMILES | CC(=O)NC(CC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NC(C(=O)NC(CC(=O)Nc1ccc([N+](=O)[O-])cc1)C(=O)O)C(C)C |