Ac-DEVD-pNA

Modify Date: 2024-07-11 14:22:52

Ac-DEVD-pNA Structure
Ac-DEVD-pNA structure
Common Name Ac-DEVD-pNA
CAS Number 189684-50-2 Molecular Weight 638.5
Density N/A Boiling Point N/A
Molecular Formula C26H34N6O13 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Ac-DEVD-pNA


Ac-DEVD-pNA is a colorimetric substrate for caspase-3 (CPP32) (Km=9.7μM) and related cysteine proteases.

 Names

Name Ac-DEVD-pNA(Caspase-3 Substrate)

 Ac-DEVD-pNA Biological Activity

Description Ac-DEVD-pNA is a colorimetric substrate for caspase-3 (CPP32) (Km=9.7μM) and related cysteine proteases.
In Vitro Ac-DEVD-pNA is a colorimetric substrate for caspase-3 (CPP32) (Km=9.7μM) and related cysteine proteases. It is also a substrate for caspase-6, caspase-7, caspase-8, and caspase-10. The sequence is based on PARP (poly(ADPribose) polymerase) cleavage site Asp216 for caspase-3. Cleavage is monitored colorimetrically at 405nm.

 Chemical & Physical Properties

Molecular Formula C26H34N6O13
Molecular Weight 638.5
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