CCG-232601
Modify Date: 2024-01-19 14:10:38
CCG-232601 structure
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Common Name | CCG-232601 | ||
|---|---|---|---|---|
| CAS Number | 1922099-21-5 | Molecular Weight | 455.884 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 683.1±55.0 °C at 760 mmHg | |
| Molecular Formula | C24H20ClF2N3O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 366.9±31.5 °C | |
Use of CCG-232601CCG-232601 is a potent (IC50=0.55 uM), orally bioavailable Rho/MKL1/SRF transcriptional pathway that target transcriptional factor MRTF; inhibits the development of bleomycin-induced dermal fibrosis in mice when administered at 50mg/kg. |
| Name | N-(4-Chlorophenyl)-5,5-difluoro-1-[3-(4-pyridinyl)benzoyl]-3-piperidinecarboxamide |
|---|---|
| Synonym | More Synonyms |
| Description | CCG-232601 is a potent (IC50=0.55 uM), orally bioavailable Rho/MKL1/SRF transcriptional pathway that target transcriptional factor MRTF; inhibits the development of bleomycin-induced dermal fibrosis in mice when administered at 50mg/kg. |
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| References | References 1. Hutchings KM, et al. Bioorg Med Chem Lett. 2017 Apr 15;27(8):1744-1749. View Related Products by Target Other Targets |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 683.1±55.0 °C at 760 mmHg |
| Molecular Formula | C24H20ClF2N3O2 |
| Molecular Weight | 455.884 |
| Flash Point | 366.9±31.5 °C |
| Exact Mass | 455.121216 |
| LogP | 3.10 |
| Vapour Pressure | 0.0±2.1 mmHg at 25°C |
| Index of Refraction | 1.636 |
| 3-Piperidinecarboxamide, N-(4-chlorophenyl)-5,5-difluoro-1-[3-(4-pyridinyl)benzoyl]- |
| N-(4-Chlorophenyl)-5,5-difluoro-1-[3-(4-pyridinyl)benzoyl]-3-piperidinecarboxamide |