GNE-502
Modify Date: 2024-01-02 19:04:07
GNE-502 structure
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Common Name | GNE-502 | ||
|---|---|---|---|---|
| CAS Number | 1953134-16-1 | Molecular Weight | 471.59 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C25H30FN3O3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of GNE-502GNE-502 is an orally active and potent degrader for estrogen receptor (ER). GNE-502 can be used for the research of breast cancer[1]. |
| Name | GNE-502 |
|---|
| Description | GNE-502 is an orally active and potent degrader for estrogen receptor (ER). GNE-502 can be used for the research of breast cancer[1]. |
|---|---|
| Related Catalog | |
| Target |
ER[1] |
| In Vivo | GNE-502 (10 and 100 mg/kg; p.o.) possesses sufficient oral exposure to be tested in a WT MCF7 tumor xenograft model[1]. ..GNE-502 shows dose dependent tumor growth inhibition at 10 mg/kg and 30 mg/kg, with tumor stasis at 100 mg/kg[1]. Animal Model: Mouse[1] Dosage: 10 and 100 mg/kg (Pharmacokinetic Analysis) Administration: P.o. Result: Possessed sufficient oral exposure to be tested in a WT MCF7 tumor xenograft model. |
| References |
| Molecular Formula | C25H30FN3O3S |
|---|---|
| Molecular Weight | 471.59 |