Thalidomide-PEG2-NH2 structure
|
Common Name | Thalidomide-PEG2-NH2 | ||
---|---|---|---|---|
CAS Number | 1957235-94-7 | Molecular Weight | 361.35 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C17H19N3O6 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of Thalidomide-PEG2-NH2Thalidomide-PEG2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. |
Name | Thalidomide-PEG2-NH2 |
---|
Description | Thalidomide-PEG2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. |
---|---|
Related Catalog | |
Target |
Cereblon |
In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
References |
Molecular Formula | C17H19N3O6 |
---|---|
Molecular Weight | 361.35 |
Hazard Codes | Xi |
---|