Thalidomide-amido-PEG2-NH2 hydrochloride
Modify Date: 2024-04-08 11:52:05
Thalidomide-amido-PEG2-NH2 hydrochloride structure
|
Common Name | Thalidomide-amido-PEG2-NH2 hydrochloride | ||
|---|---|---|---|---|
| CAS Number | 2380273-73-2 | Molecular Weight | 454.86 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H23ClN4O7 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Thalidomide-amido-PEG2-NH2 hydrochlorideThalidomide-amido-PEG2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. |
| Name | Thalidomide-amido-PEG2-NH2 hydrochloride |
|---|---|
| Synonym | More Synonyms |
| Description | Thalidomide-amido-PEG2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. |
|---|---|
| Related Catalog | |
| Target |
Cereblon |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
| References |
| Molecular Formula | C19H23ClN4O7 |
|---|---|
| Molecular Weight | 454.86 |
| Hazard Codes | Xi |
|---|
| MFCD32173780 |