HSP90-IN-14

Modify Date: 2024-01-17 17:58:25

HSP90-IN-14 structure	Common Name	HSP90-IN-14
	CAS Number	1995132-67-6	Molecular Weight	399.21
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₄H₈Cl₂N₄O₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of HSP90-IN-14

HSP90-IN-14 (compound 4) is a potent Hsp90 (heat shock protein 90) inhibitor, with a Kd of 0.26 μM. HSP90-IN-14 shows anti-influenza virus activity in MDCK cells, with EC50 values of 2.6, 3.9, and 17 μM for influenza A/H3N2, A/H1N1, and B, respectively[1].

Name	HSP90-IN-14

Description	HSP90-IN-14 (compound 4) is a potent Hsp90 (heat shock protein 90) inhibitor, with a Kd of 0.26 μM. HSP90-IN-14 shows anti-influenza virus activity in MDCK cells, with EC50 values of 2.6, 3.9, and 17 μM for influenza A/H3N2, A/H1N1, and B, respectively[1].
Related Catalog	Signaling Pathways >> Anti-infection >> Influenza Virus Signaling Pathways >> Metabolic Enzyme/Protease >> HSP Research Areas >> Infection Signaling Pathways >> Cell Cycle/DNA Damage >> HSP
Target	HSP90β:0.26 ± 0.0 μM (Kd)
In Vitro	HSP90-IN-14 (compound 4) (50 µM) inhibits influenza virus-induced cytopathic effect at non-toxic concentrations[1].
References	[1]. Lamut A, et al. Anti-influenza virus activity of benzo[d]thiazoles that target heat shock protein 90. Bioorg Chem. 2020 May;98:103733.

Molecular Formula	C₁₄H₈Cl₂N₄O₄S
Molecular Weight	399.21

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

HSP90-IN-14

Use of HSP90-IN-14

Names

HSP90-IN-14 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.