HSP90-IN-12

Modify Date: 2024-04-18 19:54:00

HSP90-IN-12 Structure
HSP90-IN-12 structure
Common Name HSP90-IN-12
CAS Number 2408643-60-5 Molecular Weight 400.55
Density N/A Boiling Point N/A
Molecular Formula C25H36O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of HSP90-IN-12


Among vibsanin a analogues, vibsanin a analog C (VAC) showed anti proliferative effect on various cancer cell lines, and the anti proliferative activity was the strongest among vibsanin a analogues. In addition, VAC fluctuated the amount of hsp90 related proteins in cells and inhibited hsp90 mediated protein refolding of luciferase in vitro.

 Names

Name HSP90-IN-12

 HSP90-IN-12 Biological Activity

Description Among vibsanin a analogues, vibsanin a analog C (VAC) showed anti proliferative effect on various cancer cell lines, and the anti proliferative activity was the strongest among vibsanin a analogues. In addition, VAC fluctuated the amount of hsp90 related proteins in cells and inhibited hsp90 mediated protein refolding of luciferase in vitro.
Related Catalog
References

[1]. Miura K,et al. Identification of vibsanin A analog as a novel HSP90 inhibitor. Bioorg Med Chem. 2020 Jan 15;28(2):115253.

 Chemical & Physical Properties

Molecular Formula C25H36O4
Molecular Weight 400.55
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