PF-4363467
Modify Date: 2023-02-02 11:34:23
PF-4363467 structure
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Common Name | PF-4363467 | ||
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| CAS Number | 2040055-84-1 | Molecular Weight | 402.553 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H30N2O3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PF-4363467PF-4363467 (PF 04363467) is a novel highly potent, brain penetrant dopamine D3/D2 receptor antagonist with Ki of 1.3/692 nM respectively, with high selectivity for D3R versus other biogenic amine receptors; dose-dependently attenuated opioid self-administration and opioid drug-seeking behavior in a rat operant reinstatement model using animals trained to self-administer fentanyl. |
| Name | PF-4363467 |
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| Description | PF-4363467 (PF 04363467) is a novel highly potent, brain penetrant dopamine D3/D2 receptor antagonist with Ki of 1.3/692 nM respectively, with high selectivity for D3R versus other biogenic amine receptors; dose-dependently attenuated opioid self-administration and opioid drug-seeking behavior in a rat operant reinstatement model using animals trained to self-administer fentanyl. |
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| References | References 1. Wager TT, et al. ACS Chem Neurosci. 2017 Jan 18;8(1):165-177. View Related Products by Target Dopamine Receptor |
| Molecular Formula | C22H30N2O3S |
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| Molecular Weight | 402.553 |