Ald-Ph-PEG2-amine TFA

Modify Date: 2023-01-17 15:55:31

Ald-Ph-PEG2-amine TFA Structure
Ald-Ph-PEG2-amine TFA structure
Common Name Ald-Ph-PEG2-amine TFA
CAS Number 2055013-56-2 Molecular Weight 280.32
Density N/A Boiling Point N/A
Molecular Formula C14H20N2O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Ald-Ph-PEG2-amine TFA


Ald-Ph-amido-C2-PEG2-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Ald-Ph-amido-C2-PEG2-amine

 Ald-Ph-PEG2-amine TFA Biological Activity

Description Ald-Ph-amido-C2-PEG2-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C14H20N2O4
Molecular Weight 280.32