3,4-Dibromo-Mal-PEG2-amine TFA

Modify Date: 2025-08-26 15:53:32

3,4-Dibromo-Mal-PEG2-amine TFA structure	Common Name	3,4-Dibromo-Mal-PEG2-amine TFA
	CAS Number	2296708-07-9	Molecular Weight	500.06
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₂H₁₅Br₂F₃N₂O₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 3,4-Dibromo-Mal-PEG2-amine TFA

3,4-Dibromo-Mal-PEG2-amine TFA is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	3,4-Dibromo-Mal-PEG2-amine TFA

Description	3,4-Dibromo-Mal-PEG2-amine TFA is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₁₂H₁₅Br₂F₃N₂O₆
Molecular Weight	500.06
InChIKey	MGVSSFASAOVDDG-UHFFFAOYSA-N
SMILES	NCCOCCOCCN1C(=O)C(Br)=C(Br)C1=O.O=C(O)C(F)(F)F

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China
Product Name: 3,4-Dibromo-Mal-PEG2-amine TFA
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Purity: 98.0%
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