Aminooxy-PEG8-acid

Modify Date: 2024-01-10 12:36:04

Aminooxy-PEG8-acid Structure
Aminooxy-PEG8-acid structure
Common Name Aminooxy-PEG8-acid
CAS Number 2055013-68-6 Molecular Weight 457.51
Density N/A Boiling Point N/A
Molecular Formula C19H39NO11 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Aminooxy-PEG8-acid


Aminooxy-PEG8-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Aminooxy-PEG8-acid

 Aminooxy-PEG8-acid Biological Activity

Description Aminooxy-PEG8-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C19H39NO11
Molecular Weight 457.51