Mal-NH-PEG8-CH2CH2COOPFP ester

Modify Date: 2024-01-31 17:34:20

Mal-NH-PEG8-CH2CH2COOPFP ester Structure
Mal-NH-PEG8-CH2CH2COOPFP ester structure
Common Name Mal-NH-PEG8-CH2CH2COOPFP ester
CAS Number 2055023-14-6 Molecular Weight 758.68
Density N/A Boiling Point N/A
Molecular Formula C32H43F5N2O13 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Mal-NH-PEG8-CH2CH2COOPFP ester


Mal-NH-PEG8-CH2CH2COOPFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Mal-NH-PEG8-CH2CH2COOPFP ester
Synonym More Synonyms

 Mal-NH-PEG8-CH2CH2COOPFP ester Biological Activity

Description Mal-NH-PEG8-CH2CH2COOPFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C32H43F5N2O13
Molecular Weight 758.68

 Safety Information

Hazard Codes Xi

 Synonyms

MFCD28385471