Propargyl-PEG4-S-PEG4-propargyl

Modify Date: 2024-01-09 19:52:18

Propargyl-PEG4-S-PEG4-propargyl Structure
Propargyl-PEG4-S-PEG4-propargyl structure
Common Name Propargyl-PEG4-S-PEG4-propargyl
CAS Number 2055041-17-1 Molecular Weight 462.60
Density N/A Boiling Point N/A
Molecular Formula C22H38O8S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Propargyl-PEG4-S-PEG4-propargyl


Propargyl-PEG4-S-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Propargyl-PEG4-S-PEG4-propargyl
Synonym More Synonyms

 Propargyl-PEG4-S-PEG4-propargyl Biological Activity

Description Propargyl-PEG4-S-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C22H38O8S
Molecular Weight 462.60

 Synonyms

MFCD29918246