Boc-NH-PEG7-NH2

Modify Date: 2024-01-05 13:43:26

Boc-NH-PEG7-NH2 Structure
Boc-NH-PEG7-NH2 structure
 Common Name Boc-NH-PEG7-NH2
CAS Number 206265-98-7 Molecular Weight 468.58200
Density 1.075g/cm3 Boiling Point 547.7ºC at 760 mmHg
Molecular Formula C21H44N2O9 Melting Point N/A
MSDS USA Flash Point 285ºC

 Use of Boc-NH-PEG7-NH2


Boc-NH-PEG7-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name tert-butyl N-[2-[2-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]carbamate
Synonym More Synonyms

 Boc-NH-PEG7-NH2 Biological Activity

Description Boc-NH-PEG7-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.075g/cm3
Boiling Point 547.7ºC at 760 mmHg
Molecular Formula C21H44N2O9
Molecular Weight 468.58200
Flash Point 285ºC
Exact Mass 468.30500
PSA 128.96000
LogP 1.67720
Vapour Pressure 4.75E-12mmHg at 25°C
Index of Refraction 1.464

 Safety Information

Personal Protective Equipment Eyeshields;Gloves
RIDADR NONH for all modes of transport
WGK Germany 3

 Precursor & DownStream

Precursor  0

DownStream  1

 Synonyms

Boc-NH-PEG7-CH2CH2NH2
25-Amino-5,8,11,14,17,20,23-heptaoxa-2-azapentacosanoic Acid1,1-Dimethylethyl Ester
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