4'-O-Methylbroussochalcone B

Modify Date: 2024-01-04 09:08:15

4'-O-Methylbroussochalcone B structure	Common Name	4'-O-Methylbroussochalcone B
	CAS Number	20784-60-5	Molecular Weight	338.397
	Density	1.2±0.1 g/cm3	Boiling Point	552.1±50.0 °C at 760 mmHg
	Molecular Formula	C₂₁H₂₂O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	194.9±23.6 °C

Use of 4'-O-Methylbroussochalcone B

4'-O-Methylbavachalcone is a chalcone isolated from Psoralea corylifolia, inhibits severe acute respiratory syndrome coronavirus (SARS-CoV) papain-like protease (PLpro) activity, with an IC50 of 10.1 μM[1].

Name	(2E)-1-[2-Hydroxy-4-methoxy-5-(3-methyl-2-buten-1-yl)phenyl]-3-(4 -hydroxyphenyl)-2-propen-1-one
Synonym	More Synonyms

Description	4'-O-Methylbavachalcone is a chalcone isolated from Psoralea corylifolia, inhibits severe acute respiratory syndrome coronavirus (SARS-CoV) papain-like protease (PLpro) activity, with an IC50 of 10.1 μM[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> SARS-CoV
Target	IC50: 10.1 μM (PLpro)[1]
References	[1]. 4'-O-Methylbavachalcone, et al. Phenolic phytochemical displaying SARS-CoV papain-like protease inhibition from the seeds of Psoralea corylifolia. J Enzyme Inhib Med Chem. 2014 Feb;29(1):59-63.

Density	1.2±0.1 g/cm3
Boiling Point	552.1±50.0 °C at 760 mmHg
Molecular Formula	C₂₁H₂₂O₄
Molecular Weight	338.397
Flash Point	194.9±23.6 °C
Exact Mass	338.151794
PSA	66.76000
LogP	5.84
Vapour Pressure	0.0±1.5 mmHg at 25°C
Index of Refraction	1.622

Hazard Codes	Xi

N/A

CAS#:128961-13-7

~82%

4'-O-Methylbrou...

CAS#:20784-60-5

Literature: Sugamoto, Kazuhiro; Matsusita, Yoh-Ichi; Matsui, Kana; Kurogi, Chiaki; Matsui, Takanao Tetrahedron, 2011 , vol. 67, # 29 p. 5346 - 5359

N/A

CAS#:28448-83-1

4-hydroxybenzal...

CAS#:123-08-0

4'-O-Methylbrou...

CAS#:20784-60-5

Literature: TAKARA BIO INC. Patent: EP1623704 A1, 2006 ; Location in patent: Page/Page column 59 ;

4'-methoxy-4-me...

CAS#:1092462-95-7

4'-O-Methylbrou...

CAS#:20784-60-5

Literature: Sugamoto, Kazuhiro; Matsusita, Yoh-Ichi; Matsui, Kana; Kurogi, Chiaki; Matsui, Takanao Tetrahedron, 2011 , vol. 67, # 29 p. 5346 - 5359

Paeonol

CAS#:552-41-0

4'-O-Methylbrou...

CAS#:20784-60-5

Literature: Sugamoto, Kazuhiro; Matsusita, Yoh-Ichi; Matsui, Kana; Kurogi, Chiaki; Matsui, Takanao Tetrahedron, 2011 , vol. 67, # 29 p. 5346 - 5359

4-(methoxymetho...

CAS#:6515-21-5

4'-O-Methylbrou...

CAS#:20784-60-5

Literature: Sugamoto, Kazuhiro; Matsusita, Yoh-Ichi; Matsui, Kana; Kurogi, Chiaki; Matsui, Takanao Tetrahedron, 2011 , vol. 67, # 29 p. 5346 - 5359

1-(4-methoxy-2-...

CAS#:128961-25-1

4'-O-Methylbrou...

CAS#:20784-60-5

Literature: Sugamoto, Kazuhiro; Matsusita, Yoh-Ichi; Matsui, Kana; Kurogi, Chiaki; Matsui, Takanao Tetrahedron, 2011 , vol. 67, # 29 p. 5346 - 5359

4-hydroxybenzal...

CAS#:123-08-0

4'-O-Methylbrou...

CAS#:20784-60-5

Literature: Sugamoto, Kazuhiro; Matsusita, Yoh-Ichi; Matsui, Kana; Kurogi, Chiaki; Matsui, Takanao Tetrahedron, 2011 , vol. 67, # 29 p. 5346 - 5359

Precursor 5
CAS#:123-08-0 4-hydroxybenzal... CAS#:1092462-95-7 4'-methoxy-4-me... CAS#:552-41-0 Paeonol CAS#:6515-21-5 4-(methoxymetho...
CAS#:128961-25-1 1-(4-methoxy-2-...
DownStream 0

batracyclin

4,2'-dihydroxy-4'-methoxy-5'-prenylchalcone

2-Propen-1-one, 1-[2-hydroxy-4-methoxy-5-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-, (2E)-

(2E)-1-[2-Hydroxy-4-methoxy-5-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one

bavachalcone

Batracylin

4'-O-Methyl-bavachalcon

Daniquidone

(2E)-1-[2-Hydroxy-4-methoxy-5-(3-methylbut-2-en-1-yl)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one

4'-O-Methylbroussochalcone B

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4'-O-Methylbroussochalcone B

Use of 4'-O-Methylbroussochalcone B

Names

4'-O-Methylbroussochalcone B Biological Activity

Chemical & Physical Properties

Safety Information

Synthetic Route

Precursor & DownStream

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.