Bcl-2/Mcl-1-IN-3

Modify Date: 2024-01-30 17:53:06

Bcl-2/Mcl-1-IN-3 Structure
Bcl-2/Mcl-1-IN-3 structure
Common Name Bcl-2/Mcl-1-IN-3
CAS Number 2088981-53-5 Molecular Weight 463.95
Density N/A Boiling Point N/A
Molecular Formula C27H26ClNO4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bcl-2/Mcl-1-IN-3


Bcl-2/Mcl-1-IN-3 (compound 1) is a Bcl-2/Mcl-1 inhibitor, with Kis of 0.14 μM and 0.23 μM for Mcl-1 and Bcl-2, respectively. Bcl-2/Mcl-1-IN-3 can be used for the research of cancer[1].

 Names

Name Bcl-2/Mcl-1-IN-3

 Bcl-2/Mcl-1-IN-3 Biological Activity

Description Bcl-2/Mcl-1-IN-3 (compound 1) is a Bcl-2/Mcl-1 inhibitor, with Kis of 0.14 μM and 0.23 μM for Mcl-1 and Bcl-2, respectively. Bcl-2/Mcl-1-IN-3 can be used for the research of cancer[1].
Related Catalog
Target

Mcl-1:0.14 μM (Ki)

Bcl-2:0.23 μM (Ki)

Bcl-xL:15 μM (Ki)

References

[1]. Niu Q, et, al. Design, synthesis and biological evaluation of dual Bcl-2/Mcl-1 inhibitors bearing 2-(1H-indol-4-yl)benzoic acid scaffold. Bioorg Med Chem Lett. 2021 Sep 1;47:128215.

 Chemical & Physical Properties

Molecular Formula C27H26ClNO4
Molecular Weight 463.95
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