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2673361-07-2

2673361-07-2 structure
2673361-07-2 structure
  • Name: Bcl-2/Mcl-1-IN-2
  • Chemical Name: Bcl-2/Mcl-1-IN-2
  • CAS Number: 2673361-07-2
  • Molecular Formula: C26H24ClNO3
  • Molecular Weight: 433.93
  • Create Date: 2022-05-15 17:45:22
  • Modify Date: 2024-01-03 19:58:17
  • Bcl-2/Mcl-1-IN-2 (compound 2) is a Bcl-2/Mcl-1 inhibitor, with Kis of 0.88 μM and 4.70 μM for Mcl-1 and Bcl-2, respectively. Bcl-2/Mcl-1-IN-2 can be used for the research of cancer[1].

Name Bcl-2/Mcl-1-IN-2
Description Bcl-2/Mcl-1-IN-2 (compound 2) is a Bcl-2/Mcl-1 inhibitor, with Kis of 0.88 μM and 4.70 μM for Mcl-1 and Bcl-2, respectively. Bcl-2/Mcl-1-IN-2 can be used for the research of cancer[1].
Related Catalog
Target

Mcl-1:0.88 μM (Ki)

Bcl-2:4.70 μM (Ki)

References

[1]. Niu Q, et, al. Design, synthesis and biological evaluation of dual Bcl-2/Mcl-1 inhibitors bearing 2-(1H-indol-4-yl)benzoic acid scaffold. Bioorg Med Chem Lett. 2021 Sep 1;47:128215.

Molecular Formula C26H24ClNO3
Molecular Weight 433.93