Bcl-2/Mcl-1-IN-2

Modify Date: 2025-08-26 07:43:28

Bcl-2/Mcl-1-IN-2 Structure
Bcl-2/Mcl-1-IN-2 structure
Common Name Bcl-2/Mcl-1-IN-2
CAS Number 2673361-07-2 Molecular Weight 433.93
Density N/A Boiling Point N/A
Molecular Formula C26H24ClNO3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bcl-2/Mcl-1-IN-2


Bcl-2/Mcl-1-IN-2 (compound 2) is a Bcl-2/Mcl-1 inhibitor, with Kis of 0.88 μM and 4.70 μM for Mcl-1 and Bcl-2, respectively. Bcl-2/Mcl-1-IN-2 can be used for the research of cancer[1].

 Names

Name Bcl-2/Mcl-1-IN-2

 Bcl-2/Mcl-1-IN-2 Biological Activity

Description Bcl-2/Mcl-1-IN-2 (compound 2) is a Bcl-2/Mcl-1 inhibitor, with Kis of 0.88 μM and 4.70 μM for Mcl-1 and Bcl-2, respectively. Bcl-2/Mcl-1-IN-2 can be used for the research of cancer[1].
Related Catalog
Target

Mcl-1:0.88 μM (Ki)

Bcl-2:4.70 μM (Ki)

References

[1]. Niu Q, et, al. Design, synthesis and biological evaluation of dual Bcl-2/Mcl-1 inhibitors bearing 2-(1H-indol-4-yl)benzoic acid scaffold. Bioorg Med Chem Lett. 2021 Sep 1;47:128215.

 Chemical & Physical Properties

Molecular Formula C26H24ClNO3
Molecular Weight 433.93
InChIKey WVQDCJUWBRZUKS-UHFFFAOYSA-N
SMILES Cc1cc(OCCCn2ccc3c(-c4ccccc4C(=O)O)cccc32)cc(C)c1Cl
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