Bcl-2/Mcl-1-IN-1

Modify Date: 2024-01-28 18:45:44

Bcl-2/Mcl-1-IN-1 Structure
Bcl-2/Mcl-1-IN-1 structure
Common Name Bcl-2/Mcl-1-IN-1
CAS Number 2673361-08-3 Molecular Weight 421.49
Density N/A Boiling Point N/A
Molecular Formula C28H23NO3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bcl-2/Mcl-1-IN-1


Bcl-2/Mcl-1-IN-1 (compound 3) is a Bcl-2/Mcl-1 inhibitor, with Kis of 1.19 μM and 4.53 μM for Mcl-1 and Bcl-2, respectively. Bcl-2/Mcl-1-IN-1 can be used for the research of cancer[1].

 Names

Name Bcl-2/Mcl-1-IN-1

 Bcl-2/Mcl-1-IN-1 Biological Activity

Description Bcl-2/Mcl-1-IN-1 (compound 3) is a Bcl-2/Mcl-1 inhibitor, with Kis of 1.19 μM and 4.53 μM for Mcl-1 and Bcl-2, respectively. Bcl-2/Mcl-1-IN-1 can be used for the research of cancer[1].
Related Catalog
Target

Mcl-1:1.19 μM (Ki)

Bcl-2:4.53 μM (Ki)

References

[1]. Niu Q, et, al. Design, synthesis and biological evaluation of dual Bcl-2/Mcl-1 inhibitors bearing 2-(1H-indol-4-yl)benzoic acid scaffold. Bioorg Med Chem Lett. 2021 Sep 1;47:128215.

 Chemical & Physical Properties

Molecular Formula C28H23NO3
Molecular Weight 421.49
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