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2673361-08-3

2673361-08-3 structure
2673361-08-3 structure
  • Name: Bcl-2/Mcl-1-IN-1
  • Chemical Name: Bcl-2/Mcl-1-IN-1
  • CAS Number: 2673361-08-3
  • Molecular Formula: C28H23NO3
  • Molecular Weight: 421.49
  • Create Date: 2022-05-16 12:36:52
  • Modify Date: 2024-01-28 18:45:44
  • Bcl-2/Mcl-1-IN-1 (compound 3) is a Bcl-2/Mcl-1 inhibitor, with Kis of 1.19 μM and 4.53 μM for Mcl-1 and Bcl-2, respectively. Bcl-2/Mcl-1-IN-1 can be used for the research of cancer[1].

Name Bcl-2/Mcl-1-IN-1
Description Bcl-2/Mcl-1-IN-1 (compound 3) is a Bcl-2/Mcl-1 inhibitor, with Kis of 1.19 μM and 4.53 μM for Mcl-1 and Bcl-2, respectively. Bcl-2/Mcl-1-IN-1 can be used for the research of cancer[1].
Related Catalog
Target

Mcl-1:1.19 μM (Ki)

Bcl-2:4.53 μM (Ki)

References

[1]. Niu Q, et, al. Design, synthesis and biological evaluation of dual Bcl-2/Mcl-1 inhibitors bearing 2-(1H-indol-4-yl)benzoic acid scaffold. Bioorg Med Chem Lett. 2021 Sep 1;47:128215.

Molecular Formula C28H23NO3
Molecular Weight 421.49